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Colorectal cancer (CRC) is cancer that develops in the colon or the rectum-parts of the digestive system also called the gastrointestinal or GI tract. The digestive system processes food for energy and rids the body of solid waste. Colorectal cancer usually develops slowly over a period of many years. Before a true cancer develops, it usually begins as a non-cancerous polyp, a growth of tissue that develops on the lining of the colon or rectum. Certain kinds of polyps, called adenomas, are most likely to become cancerous.